Primary malignant mixed müllerian tumor of the ovary

Taiwan J Obstet Gynecol. 2010 Mar;49(1):87-90. doi: 10.1016/S1028-4559(10)60016-2.

Abstract

Objective: To present a case of malignant mixed müllerian tumor of the ovary, a rare and aggressive ovarian malignant tumor with poor prognosis.

Case report: A 52-year-old woman consulted our outpatient department with complaints of abdominal distention and a firm palpable mass over her lower abdomen. Physical examination and computerized tomography revealed cystic mass lesions on the bilateral adnexal areas. Ovarian cancer was suspected, so the patient underwent exploratory laparotomy. Optimal debulking surgery was performed, and final pathology revealed malignant mixed müllerian tumor of the ovary. Chemotherapy using ifosfamide and cisplatin were administered postoperatively, and adjuvant was also administered. After six cycles of chemotherapy, the patient is well with no signs of recurrence.

Conclusion: Ovarian malignant mixed müllerian tumor usually yields poor outcomes; hence, aggressive treatment with optimal debulking surgery followed by combination chemotherapy using ifosfamide and cisplatin may improve patient outcomes.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents / therapeutic use
  • Chemotherapy, Adjuvant
  • Cisplatin / therapeutic use
  • Female
  • Humans
  • Ifosfamide / therapeutic use
  • Middle Aged
  • Mixed Tumor, Mullerian / pathology*
  • Mixed Tumor, Mullerian / therapy
  • Ovarian Neoplasms / pathology*
  • Ovarian Neoplasms / therapy

Substances

  • Antineoplastic Agents
  • Cisplatin
  • Ifosfamide