Abstract
Protein engineering has made it possible to combine the binding sites of murine antibodies with human antibody regions. Antibodies constructed in this way have important advantages for therapy.
MeSH terms
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Animals
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Antibodies, Monoclonal / genetics
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Antibodies, Monoclonal / immunology
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Antibodies, Monoclonal / therapeutic use*
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Antigens / immunology
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Binding Sites, Antibody / genetics
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Humans
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Lymphocytes / immunology
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Mice
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Protein Engineering*
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Recombinant Proteins / therapeutic use
Substances
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Antibodies, Monoclonal
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Antigens
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Recombinant Proteins