Abstract
A new cadinane-type sesquiterpenoid, tatarinowin A (1), two phenylpropanoids, tatarinoids A (2) and B (3), and a trinorlignan, tatarinoid C (4), along with 15 known compounds including two pairs of mixtures were isolated from the rhizome of Acorus tatarinowii. The absolute configurations of 1-4 were established by computation of specific rotation values. The isolated compounds were evaluated for their cAMP regulatory activity by the AlphaScreen assay.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acorus / chemistry*
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Cyclic AMP / metabolism*
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Drugs, Chinese Herbal / chemistry
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Drugs, Chinese Herbal / isolation & purification*
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Drugs, Chinese Herbal / pharmacology
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Lignans / chemistry
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Lignans / isolation & purification*
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Lignans / pharmacology
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Molecular Structure
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Phenylpropionates / chemistry
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Phenylpropionates / isolation & purification*
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Phenylpropionates / pharmacology
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Rhizome / chemistry
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Sesquiterpenes / chemistry
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Sesquiterpenes / isolation & purification*
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Sesquiterpenes / pharmacology*
Substances
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Drugs, Chinese Herbal
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Lignans
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Phenylpropionates
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Sesquiterpenes
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Cyclic AMP