Epidermotropic metastatic mucoepidermoid carcinoma

Am J Dermatopathol. 2010 Jul;32(5):505-8. doi: 10.1097/DAD.0b013e3181c956e1.

Abstract

Mucoepidermoid carcinoma (MEC), an invasive malignant neoplasm composed of mucus-secreting, epidermoid, and intermediate cells in varying proportions, is the commonest malignant salivary gland neoplasm in adults. Cutaneous metastases from the same, although not entirely common, has been previously reported but are typically confined to dermis. In this report, we present a case of MEC presenting as a cutaneous metastasis. A histologic feature unique to this case was epidermotropism, previously not noted in either metastatic or primary MEC.

Publication types

  • Case Reports

MeSH terms

  • Adrenal Gland Neoplasms / secondary
  • Biopsy
  • Carcinoma, Mucoepidermoid / secondary*
  • Cerebellar Neoplasms / secondary
  • Diagnosis, Differential
  • Epidermis / pathology*
  • Humans
  • Liver Neoplasms / secondary
  • Lung Neoplasms / secondary
  • Male
  • Middle Aged
  • Salivary Gland Neoplasms / pathology*
  • Skin Neoplasms / secondary*