Excerpt
Proton pump inhibitors (PPIs) decrease gastric acid and gastric secretory volume. PPIs are used to treat peptic ulcers (duodenal and gastric), symptoms of gastroesophageal reflux disease (GERD), erosive esophagitis, and drug-induced ulcers (e.g., non-steroidal anti-inflammatory drugs {NSAIDs}). The purpose of this review is to compare the benefits and harms of different PPIs.
Copyright © 2006, Oregon Health & Science University, Portland, Oregon.
Grants and funding
The funding source, the Center for Evidence-based Policy, is supported by 17 organizations, including 15 state Medicaid programs. These organizations selected the topic and had input into the Key Questions for this review. The content and conclusions of the review are entirely determined by the Evidence-based Practice Center researchers. The authors of this report have no financial interest in any company that makes or distributes the products reviewed in this report.