Growing attention has focused on meaning-making processes and their health correlates among cancer patients. However, much of this work is marked by conceptual and methodological limitations. The current study evaluated global meaning and theoretically distinct aspects of illness-specific meaning (i.e., seeking sense, found sense, seeking benefits, found benefits) among breast cancer survivors who had completed primary treatment. Health outcomes (i.e., emotional distress, health-related quality-of-life) were assessed 4 months later. Different facets of meaning had different longitudinal associations with outcomes. Findings underscore the importance of distinguishing among conceptually discrete dimensions of personal meaning.