Severe Mediterranean spotted fever complicated by acute renal failure and herpetic oesophagitis

Laura Saporito; Giovanni M Giammanco; Raffaella Rubino; Daniela Ingrassia; Daria Spicola; Lucina Titone; Claudia Colomba

doi:10.1099/jmm.0.015891-0

Severe Mediterranean spotted fever complicated by acute renal failure and herpetic oesophagitis

J Med Microbiol. 2010 Aug;59(Pt 8):990-992. doi: 10.1099/jmm.0.015891-0. Epub 2010 May 27.

Authors

Laura Saporito¹, Giovanni M Giammanco², Raffaella Rubino¹, Daniela Ingrassia¹, Daria Spicola¹, Lucina Titone¹, Claudia Colomba¹

Affiliations

¹ Dipartimento di Scienze per la Promozione della Salute, Sezione di Malattie Infettive, Università di Palermo, Via del Vespro 129, 90127 Palermo, Italy.
² Dipartimento di Scienze per la Promozione della Salute, Sezione di Microbiologia, Università di Palermo, Via del Vespro 129, 90127 Palermo, Italy.

PMID: 20508004
DOI: 10.1099/jmm.0.015891-0

Abstract

Mediterranean spotted fever (MSF) is a tick-borne disease caused by Rickettsia conorii. Recently, complicated cases have been more frequently reported, even in previously healthy patients. We describe a case of severe MSF complicated by acute renal failure and associated with herpetic oesophagitis. Acyclovir therapy resulted in remission of oesophageal symptoms within 48 h.

Publication types

Case Reports

MeSH terms

Acute Kidney Injury / complications*
Acyclovir / therapeutic use
Antibodies, Viral / blood
Antiviral Agents / therapeutic use
Boutonneuse Fever / complications*
Esophagitis / complications*
Esophagitis / drug therapy
Herpes Simplex / complications*
Herpes Simplex / drug therapy
Herpesvirus 1, Human / isolation & purification
Humans
Male
Middle Aged
Rickettsia conorii / isolation & purification
Treatment Outcome

Substances

Antibodies, Viral
Antiviral Agents
Acyclovir