[The ventilatory response in chronic heart failure population]

Symptom-limited exercise test with peak oxygen consumption measurement possesses a strong prognostic value in chronic heart failure. This parameter allowing notably the selection of patients for heart transplant. Nevertheless, sub maximal effort and beta blocker therapy tend to limit its prognostic value. The ventilatory response evaluated by the minute ventilation - carbon dioxide production (VE/VCO2) linear regression slope during effort is generally considered to be a significant predictor of mortality and hospitalizations in HF population. An enhanced ventilatory response is correlated with a poorer prognostic. In addition, this parameter is not influenced by the intensity of the effort neither by the betablocker therapy. But, physiological determinants are not clear yet. Aim of our study is to confirm the important place of the (VE/VCO2) slope in HF patient's evaluation.