A 54-year-old female presented with dyspnea on exertion and wheezing, with a negative response to inhaled beta-2 stimulating drugs and intravenous glucocorticoids. The major values of basal spirometric study were normal; however, the morphology of the flow-volume curve showed intrathoracic obstruction of large airways, with negative response to beta stimulating drugs. The bronchial provocative test with histamine was normal. Chest radiographs only showed a mild widening of the median mediastinum with left anterior tracheal displacement. Nuclear magnetic resonance showed a right aortic arch with tracheal strangulation.