Abstract
Molecular analyses of mip and ompA genes were performed on 20 Neisseria gonorrhoeae isolates. The genes were present with a high degree of conservation in all strains. Sera from patients with urethritis or disseminated gonococcal infections were able to recognize the purified Neisseria gonorrhoeae macrophage infectivity potentiator (Ng-MIP) and Neisseria gonorrhoeae outer membrane protein A (Ng-OmpA).
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Bacterial Outer Membrane Proteins* / chemistry
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Bacterial Outer Membrane Proteins* / genetics
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Bacterial Outer Membrane Proteins* / immunology
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Bacterial Outer Membrane Proteins* / metabolism
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Bacterial Proteins* / chemistry
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Bacterial Proteins* / genetics
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Bacterial Proteins* / immunology
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Bacterial Proteins* / metabolism
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Gonorrhea / immunology
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Gonorrhea / microbiology
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Humans
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Macrophages / microbiology
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Molecular Sequence Data
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Neisseria gonorrhoeae / genetics
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Neisseria gonorrhoeae / immunology
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Neisseria gonorrhoeae / metabolism
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Neisseria gonorrhoeae / pathogenicity*
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Recombinant Proteins / genetics
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Recombinant Proteins / immunology
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Recombinant Proteins / metabolism
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Sequence Analysis, DNA
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Urethritis / immunology
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Urethritis / microbiology
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Virulence Factors* / chemistry
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Virulence Factors* / genetics
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Virulence Factors* / immunology
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Virulence Factors* / metabolism
Substances
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Bacterial Outer Membrane Proteins
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Bacterial Proteins
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Recombinant Proteins
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Virulence Factors
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OMPA outer membrane proteins
Associated data
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GENBANK/FN552013
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GENBANK/FN552014
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GENBANK/FN552015
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GENBANK/FN552016