Contribution of SMC (structural maintenance of chromosomes) and SpoIIIE to chromosome segregation in Staphylococci

J Bacteriol. 2010 Aug;192(15):4067-73. doi: 10.1128/JB.00010-10. Epub 2010 Jun 4.

Abstract

In contrast to rod-shaped bacteria, little is known about chromosomal maintenance and segregation in the spherical Staphylococcus aureus. The analysis of chromosomal segregation in smc (structural maintenance of chromosomes) and spoIIIE single and double mutants unravels differences in the chromosome dynamics in the spherical staphylococcal cells compared to the model in rods.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Proteins / metabolism*
  • Cell Cycle Proteins / genetics
  • Cell Cycle Proteins / metabolism*
  • Chromosomal Proteins, Non-Histone / genetics
  • Chromosomal Proteins, Non-Histone / metabolism*
  • Chromosome Segregation / genetics
  • Chromosome Segregation / physiology*
  • DNA, Bacterial
  • Gene Expression Regulation, Bacterial / physiology
  • Genotype
  • Mutation
  • Staphylococcus aureus / cytology
  • Staphylococcus aureus / genetics
  • Staphylococcus aureus / metabolism*
  • Structural Maintenance of Chromosome Protein 1
  • Temperature

Substances

  • Bacterial Proteins
  • Cell Cycle Proteins
  • Chromosomal Proteins, Non-Histone
  • DNA, Bacterial
  • Structural Maintenance of Chromosome Protein 1