A prospective study of febrile episodes in inpatient children on chemotherapy

Pediatr Infect Dis J. 2010 Oct;29(10):968-70. doi: 10.1097/INF.0b013e3181e32ab2.

Abstract

In 538 febrile episodes in 188 children enrolled prospectively, 62% of children were neutropenic and 86% had infection-related fever. Respiratory infection was the commonest febrile cause (60%). Bacteremia occurred more often in neutropenic than non-neutropenic episodes (20% vs. 3%) and was accompanied significantly more with shiver, lassitude, and decreased dorsum pedis pulse. About 65% of blood isolates were Gram-negative bacilli, which differs from the observations in western countries.

MeSH terms

  • Adolescent
  • Bacteremia / epidemiology
  • Bacteremia / pathology
  • Bacteria / classification
  • Bacteria / isolation & purification
  • Child
  • Child, Preschool
  • Drug Therapy / methods*
  • Female
  • Fever of Unknown Origin / complications
  • Fever of Unknown Origin / epidemiology*
  • Humans
  • Immunocompromised Host
  • Infant
  • Male
  • Neoplasms / complications*
  • Neoplasms / drug therapy*
  • Neutropenia / diagnosis
  • Neutropenia / epidemiology
  • Prospective Studies
  • Respiratory Tract Infections / epidemiology