Development of a SCAR marker by inter-simple sequence repeat for diagnosis of dwarf bunt of wheat and detection of Tilletia controversa KüHN

Folia Microbiol (Praha). 2010 May;55(3):258-64. doi: 10.1007/s12223-010-0038-1. Epub 2010 Jun 6.

Abstract

Dwarf bunt of wheat, caused by Tilletia controversa KüHN: , is a destructive disease on wheat as well as an important internationally quarantined disease in many countries. The primer ISSR818 generated a polymorphic pattern displaying a 867-bp DNA fragment specific for T. controversa. The marker was converted into a sequence characterized amplified region (SCAR), and specific primers (TCKSF3/TCKSR3) designed for use in PCR detection assays; they amplified a unique DNA fragment in all isolates of T. controversa but not in the related pathogens. The detection limit with the primer set (TCKSF3/TCKSR3) was 5 ng of DNA which could be obtained from 5.5 microg of teliospores in a 25-microL PCR reaction mixture.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • Basidiomycota / classification
  • Basidiomycota / genetics
  • Basidiomycota / isolation & purification*
  • DNA Primers / genetics
  • DNA, Fungal / chemistry
  • DNA, Fungal / genetics*
  • Molecular Sequence Data
  • Mycology / methods*
  • Plant Diseases / microbiology*
  • Polymerase Chain Reaction / methods*
  • Polymorphism, Genetic*
  • Repetitive Sequences, Nucleic Acid
  • Sensitivity and Specificity
  • Triticum / microbiology*

Substances

  • DNA Primers
  • DNA, Fungal