The acute effects of glucose ingestion on attentional control in fasting healthy older adults

Psychopharmacology (Berl). 2010 Aug;211(3):337-46. doi: 10.1007/s00213-010-1905-9. Epub 2010 Jun 18.

Abstract

Rationale: Glucose enhancing effects have been observed in older adults mainly for episodic memory, but have been under-investigated for attentional functions, which are very sensitive to aging.

Objective: The present study examined the acute effects of glucose ingestion on different attentional tasks in fasting healthy older adults.

Methods: In a between-subjects design, 44 participants (60 years and older) were randomly assigned to a glucose (50 g) or saccharin (placebo) condition after 12 h of fasting. Participants were tested on neuropsychological tests of attention (trail A and B, modified Stroop) and on a computerized dual-task.

Results: Participants in the glucose group were faster than the placebo group to complete the switching condition of the modified Stroop test (p < 0.01) and showed a smaller dual-task cost in the divided attention task (p < 0.05).

Conclusions: Glucose ingestion appears to momentarily enhance attentional performances in seniors who have fasted for 12 h in tasks requiring switching and dividing attention.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Attention / drug effects*
  • Blood Glucose / analysis
  • Executive Function / drug effects*
  • Fasting / blood
  • Fasting / psychology*
  • Female
  • Glucose / pharmacology*
  • Humans
  • Male
  • Middle Aged
  • Neuropsychological Tests

Substances

  • Blood Glucose
  • Glucose