In vitro activity of the Qoustic Wound Therapy System against planktonic and biofilm bacteria

Adv Skin Wound Care. 2010 Jul;23(7):316-20. doi: 10.1097/01.ASW.0000363557.45726.41.

Abstract

Objective: The purpose of this study was to determine whether the Qoustic Wound Therapy System (Arobella Medical, LLC, Minnetonka, Minnesota) kills planktonic bacterial cells and/or removes bacterial biofilms.

Design: The Qoustic Wound Therapy System was evaluated against Pseudomonas aeruginosa, Staphylococcus epidermidis, and Staphylococcus aureus planktonic cells and biofilms in vitro.

Main results: P aeruginosa, S epidermidis, and S aureus planktonic cells decreased by a mean of 5.10, 4.99, and 5.22 log10 colony-forming units/mL, respectively, with 4 Qoustic Wound Therapy System treatment minutes. After 10 minutes of treatment, P aeruginosa, S epidermidis, and S aureus biofilms decreased by a mean of 1.34, 1.46, and 1.02 log10 colony-forming units/cm, respectively.

Conclusion: The Qoustic Wound Therapy System, using the Qoustic Qurette, kills planktonic bacteria and reduces bacterial biofilms in vitro.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Infections / microbiology*
  • Bacterial Infections / therapy*
  • Biofilms*
  • Colony Count, Microbial
  • Humans
  • Pseudomonas aeruginosa / growth & development
  • Staphylococcus aureus / growth & development
  • Staphylococcus epidermidis / growth & development
  • Ultrasonic Therapy / instrumentation
  • Ultrasonic Therapy / methods*
  • Wound Healing*
  • Wound Infection / microbiology*
  • Wound Infection / therapy*