Anion receptors containing thiazine-1,1-dioxide heterocycles as hydrogen bond donors

Beilstein J Org Chem. 2010 May 19:6:50. doi: 10.3762/bjoc.6.50.

Abstract

The synthesis, X-ray crystal structures and anion recognition properties of two receptors containing thiazine-1,1-dioxide heterocycles as hydrogen bond donating subunits are reported. The newly synthesized receptors display much different anion selectivities in acetone-d₆ than N,N'-diphenyl-1,3-disulfonamidobenzene that was used as a comparison. The selectivity exhibited by one of the new receptors for chloride anions can be attributed to greater steric demand in the cleft formed, in part, by its terminal phenyl rings; an effect that is absent in the comparison receptor.

Keywords: anions; hydrogen bonds; receptors; sulfonamides; supramolecular chemistry.