Do we have to change the way targeted drugs are developed?

J Clin Oncol. 2010 Aug 20;28(24):e420-1; author reply e422-3. doi: 10.1200/JCO.2010.28.9918. Epub 2010 Jun 21.
No abstract available

Publication types

  • Letter

MeSH terms

  • Animals
  • Antineoplastic Agents / pharmacology*
  • Antineoplastic Agents / therapeutic use
  • Clinical Trials as Topic
  • Drug Delivery Systems
  • Drug Design*
  • Enzyme Activation / drug effects
  • Humans
  • Phosphatidylinositol 3-Kinases / metabolism
  • Proto-Oncogene Proteins c-akt / drug effects

Substances

  • Antineoplastic Agents
  • Phosphatidylinositol 3-Kinases
  • Proto-Oncogene Proteins c-akt