[Problems associated with treating ocular disease in underlying inflammatory rheumatic disease]

Z Rheumatol. 2010 Jul;69(5):393-6. doi: 10.1007/s00393-009-0580-x.
[Article in German]

Abstract

Ocular findings can be very typical for general disorders associated with rheumatological diseases. Of these ocular diseases, scleritis and uveitis are of particular significance. The present article discusses and attempts to solve the problems which can be seen when ocular inflammation is associated with rheumatological disorders. The identification of "uveitis" should not be sufficient to initiate diagnosis and therapy, but rather its localisation and, where possible, also its etiology should be known. These can usually be found with good clinical investigation and careful patient history. Only rarely are ocular and rheumatological inflammation active at the same time, as will be discussed later using HLA-B27-associated uveitis and juvenile idiopathic arthritis-associated uveitis as examples. It is important in the case of ocular inflammation that the indication for treatment be made by an ophthalmologist. Finally, the role of the rheumatologist in the treatment of this patient group will be described in detail.

Publication types

  • English Abstract
  • Introductory Journal Article

MeSH terms

  • Antibodies, Antinuclear / blood
  • Antirheumatic Agents / adverse effects
  • Antirheumatic Agents / therapeutic use*
  • Arthritis, Juvenile / diagnosis
  • Arthritis, Juvenile / drug therapy
  • Arthritis, Juvenile / immunology
  • Arthritis, Rheumatoid / diagnosis
  • Arthritis, Rheumatoid / drug therapy
  • Arthritis, Rheumatoid / immunology
  • Cooperative Behavior
  • Diagnosis, Differential
  • Germany
  • HLA-B27 Antigen / immunology
  • Humans
  • Immunosuppressive Agents / adverse effects
  • Immunosuppressive Agents / therapeutic use*
  • Interdisciplinary Communication
  • Medical History Taking
  • Patient Care Team
  • Randomized Controlled Trials as Topic
  • Rheumatic Diseases / diagnosis
  • Rheumatic Diseases / drug therapy*
  • Rheumatic Diseases / immunology
  • Uveitis / diagnosis
  • Uveitis / drug therapy*
  • Uveitis / immunology
  • Uveitis, Anterior / diagnosis
  • Uveitis, Anterior / drug therapy
  • Uveitis, Anterior / immunology

Substances

  • Antibodies, Antinuclear
  • Antirheumatic Agents
  • HLA-B27 Antigen
  • Immunosuppressive Agents