We experimentally demonstrate the vortex solitons of four-wave mixing (FWM) in multi-level atomic media created by the interference patterns with superposing three or more waves. The modulation effect of the vortex solitons is induced by the cross-Kerr nonlinear dispersion due to atomic coherence in the multi-level atomic system. These FWM vortex patterns are explained via the three-, four- and five-wave interference topologies.