Biosynthesis of medium-chain-length poly(3-hydroxyalkanoates) by volatile aromatic hydrocarbons-degrading Pseudomonas fulva TY16

Bioresour Technol. 2010 Nov;101(21):8485-8. doi: 10.1016/j.biortech.2010.06.033. Epub 2010 Jun 29.

Abstract

Pseudomonas fulva TY16 biosynthesized medium-chain-length poly(3-hydroxyalkanoates) (MCL-PHAs) containing unsaturated 3-hydroxydodecenoate unit (approximately 8-9%) when grown with volatile aromatic compounds including benzene, toluene, and ethylbenzene as sole carbon substrate. In particular, when cultivated using a continuous feeding system designed to supply toluene at a flow rate of 0.42gL(-1)h(-1) into a 7-L jar fermentor, the growth of the organism reached up to approximately 3.87gL(-1) after the 48h fed-batch fermentation, representing an accumulated cellular MCL-PHA of 58.9% by weight. The obtained MCL-PHA was a copolyester primarily consisting of 3-hydroxydecanoate (55.2%) and 3-hydroxyoctanoate (26.8%) with minor constituents being 3-hydroxyhexanoate (3.7%), 3-hydroxydodecenoate (8.2%), and 3-hydroxydodecanoate (6.1%). The present results suggest that P. fulva TY16 is a promising candidate for the biotechnological conversion of toxic petrochemical wastes to valuable biopolymers.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biodegradation, Environmental / drug effects
  • Bioreactors / microbiology
  • Caprylates / metabolism*
  • Carbon / pharmacology
  • Fermentation / drug effects
  • Hydrocarbons, Aromatic / metabolism*
  • Pseudomonas / isolation & purification
  • Pseudomonas / metabolism*
  • Volatilization / drug effects

Substances

  • Caprylates
  • Hydrocarbons, Aromatic
  • Carbon