1,10-Phenanthroline platinum(II) complex: a simple molecule for efficient G-quadruplex stabilization

Dalton Trans. 2010 Aug 21;39(31):7214-6. doi: 10.1039/c0dt00211a. Epub 2010 Jul 1.

Abstract

Two simple complexes [Pt(phen)(2)](PF(6))(2) and [Pt(bpy)(2)](PF(6))(2) exhibit high stabilization potential for G-quadruplex DNA with [Pt(phen)(2)](PF(6))(2) possessing higher capability due to its greater planarity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Circular Dichroism
  • Coordination Complexes / chemistry*
  • G-Quadruplexes*
  • Phenanthrolines / chemistry*
  • Platinum / chemistry*

Substances

  • Coordination Complexes
  • Phenanthrolines
  • Platinum
  • 1,10-phenanthroline