Abstract
With developments in the philosophy behind animal testing for carcinogenicity and toxicity, with increasing emphasis on Mode of Action analysis, the future usefulness of the 2 year rodent carcinogenesis bioassay is in doubt.
MeSH terms
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Animals
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Biological Assay*
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Biological Evolution*
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Carcinogenicity Tests / methods*
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Carcinogenicity Tests / trends*
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Carcinogens / toxicity*
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Disease Models, Animal*
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Humans
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Mice
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Neoplasms, Experimental / chemically induced
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Neoplasms, Experimental / pathology*
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Rats
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Risk Assessment
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Time Factors