Expression of E- and N-cadherin and CD44 in endometrium and hydrosalpinges from infertile women

Fertil Steril. 2010 Dec;94(7):2909-12. doi: 10.1016/j.fertnstert.2010.04.055. Epub 2010 Jun 3.

Abstract

In this prospective comparative study, compared with fertile control subjects (n = 12), infertile patients with hydrosalpinx (n = 18) had lower E-cadherin and a trend toward decreased N-cadherin H-scores in the endometrium (3.6 ± 0.6 vs. 2.4 ± 0.8 and 0.57 ± 1.0 vs. 0.52 ± 0.5, respectively). In hydrosalpinx, epithelial N-cadherin expression was discontinuous and disappeared in atrophic patches.

Publication types

  • Comparative Study

MeSH terms

  • Antigens, CD / metabolism*
  • Atrophy / metabolism
  • Biopsy
  • Cadherins / metabolism*
  • Case-Control Studies
  • Endometrium / metabolism*
  • Endometrium / pathology
  • Fallopian Tube Diseases / metabolism*
  • Fallopian Tube Diseases / pathology
  • Fallopian Tubes / metabolism
  • Fallopian Tubes / pathology
  • Female
  • Humans
  • Hyaluronan Receptors / metabolism*
  • Infertility, Female / metabolism*
  • Infertility, Female / pathology

Substances

  • Antigens, CD
  • CD44 protein, human
  • CDH2 protein, human
  • Cadherins
  • Hyaluronan Receptors