Pemetrexed pathway-associated germline polymorphisms: a useful tool for treatment individualization?

MeSH terms

• Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
• Biomarkers, Tumor / genetics*
• Carcinoma, Non-Small-Cell Lung / drug therapy*
• Carcinoma, Non-Small-Cell Lung / genetics
• Carcinoma, Non-Small-Cell Lung / mortality
• Carcinoma, Non-Small-Cell Lung / pathology
• Clinical Trials, Phase II as Topic
• Disease-Free Survival
• Gene Expression Regulation, Neoplastic
• Genetic Testing*
• Glutamates / administration & dosage
• Guanine / administration & dosage
• Guanine / analogs & derivatives
• Humans
• Lung Neoplasms / drug therapy*
• Lung Neoplasms / genetics
• Lung Neoplasms / mortality
• Lung Neoplasms / pathology
• Patient Selection
• Pemetrexed
• Polymorphism, Genetic*
• Precision Medicine*
• Predictive Value of Tests
• Randomized Controlled Trials as Topic
• Treatment Outcome