Matrix revolutions: a trinity of defined substrates for long-term expansion of human ESCs

Samira M Azarin; Sean P Palecek

doi:10.1016/j.stem.2010.06.008

Matrix revolutions: a trinity of defined substrates for long-term expansion of human ESCs

Cell Stem Cell. 2010 Jul 2;7(1):7-8. doi: 10.1016/j.stem.2010.06.008.

Authors

Samira M Azarin¹, Sean P Palecek

Affiliation

¹ Department of Chemical & Biological Engineering, University of Wisconsin-Madison, WI 53706, USA.

PMID: 20621041
DOI: 10.1016/j.stem.2010.06.008

Abstract

Recently in Nature Biotechnology, Rodin et al. (2010), Melkoumian et al. (2010), and Villa-Diaz et al. (2010) described defined, nonxenogenic substrates that support long-term self-renewal of human embryonic stem cells (hESCs). Used in conjunction with defined media, these substrates will facilitate expansion of hESCs for therapeutic applications.

Publication types

Comment