Study of bone mineral density in resident doctors working at a teaching hospital

J Postgrad Med. 2010 Apr-Jun;56(2):65-70. doi: 10.4103/0022-3859.65272.

Abstract

Context: The erratic lifestyle of resident doctors may affect their serum 25-hydroxy vitamin D [25-(OH)D] levels and bone mineral density (BMD).

Aim: To study BMD and the effect of environmental factors on it in resident doctors.

Settings and design: Prospective, cross-sectional study conducted in a tertiary healthcare centre.

Materials and methods: BMD was obtained by dual-energy X-ray absorptiometry and was correlated with various factors including weight, height, body mass index (BMI), sun exposure, physical activity, parathyroid hormone, 25-(OH)D, dietary factors. Statistical Analysis : SPSS software Version 10 (Unpaired t test was used to compare BMD of different groups and Pearson's correlation coefficient was used to calculate correlation).

Results: Two hundred and fourteen apparently healthy resident doctors were enrolled in the study. Based on Caucasian normative data, osteopenia was noted in 104 (59.7%) males and 27 (67.5%) females. Thirty-two (18.39%) males and five (12.5%) females had osteoporosis. The BMD values of males were 0.947+/-0.086, 0.911+/-0.129 and 1.016+/-0.133 at lumbar spine, femur neck and total hip while those in females were 0.981+/-0.092, 0.850+/-0.101 and 0.957+/-0.103 respectively. BMD of our cohort was lesser by 12.5-18.2% and 4.2-14.5% than the Caucasian and available Indian figures, respectively. BMD had significant positive correlation with weight, height, BMI, physical activity, and dietary calcium phosphorus ratio. 25-(OH)D levels were insufficient in 175 (87.5%) subjects but had no correlation with BMD.

Conclusions: Young healthy resident doctors had significantly lower BMD, contributors being lower BMI, lower height, reduced bioavailability of dietary calcium and inadequate physical activity. Deficiency of vitamin D did not contribute to low BMD.

MeSH terms

  • Absorptiometry, Photon
  • Adult
  • Body Mass Index*
  • Bone Density / physiology*
  • Calcium / blood
  • Cross-Sectional Studies
  • Exercise / physiology
  • Female
  • Hip / physiology
  • Hospitals, Teaching
  • Humans
  • India
  • Lumbar Vertebrae / physiology
  • Male
  • Parathyroid Hormone / blood
  • Physicians / statistics & numerical data*
  • Prospective Studies
  • Risk Factors
  • Sunlight
  • Vitamin D / blood
  • Young Adult

Substances

  • Parathyroid Hormone
  • Vitamin D
  • Calcium