Focal segmental glomerulosclerosis in association with Gitelman syndrome

Int Urol Nephrol. 2011 Sep;43(3):905-7. doi: 10.1007/s11255-010-9802-z. Epub 2010 Jul 14.

Abstract

Gitelman syndrome (GS) is an autosomal recessive disorder characterized by hypokalemia, metabolic alkalosis, hypomagnesemia and hypocalciuria. Glomerulonephritis associated with GS is rarely documented in the literature. We present an adult patient with GS whose renal biopsy revealed focal segmental glomerulosclerosis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Dietary Supplements
  • Diuretics / therapeutic use
  • Gitelman Syndrome / complications*
  • Gitelman Syndrome / drug therapy
  • Glomerulosclerosis, Focal Segmental / complications*
  • Glomerulosclerosis, Focal Segmental / drug therapy
  • Glomerulosclerosis, Focal Segmental / pathology*
  • Humans
  • Magnesium Chloride / therapeutic use
  • Male
  • Potassium / therapeutic use
  • Spironolactone / therapeutic use

Substances

  • Diuretics
  • Magnesium Chloride
  • Spironolactone
  • Potassium