The authors report three cases revealed by tabes arthropathy in patients younger than 45 years. The age of patients was respectively 42, 40, 42. The clinical symptoms consisted of a painless knee strain, isolated in one case, associated with radiculocordonal posterior syndrome in two cases. The radiological lesions showed bone destruction. The biological assessment was for a venereal disease. The outcome was disappointing, despite a well conducted treatment. The observation of such cases should suggest a syphilitic origin ahead any advanced painless arthropathy even in young patients.