Erythema elevatum diutinum in systemic lupus erythematosus

Rheumatol Int. 2011 Feb;31(2):259-62. doi: 10.1007/s00296-010-1574-3. Epub 2010 Jul 23.

Abstract

Erythema elevatum diutinum (EED) is a rare chronic form of leukocytoclastic vasculitis with unknown etiology. EED has been described in association with hematological malignancies, infections and a number of rheumatological diseases. We report a patient with systemic lupus erythematosus (SLE) who presented with intermittent attacks of tender nodules and plaques on the shins and ankles for 6 months. Skin biopsy confirmed the diagnosis of EED. Treatment with dapsone resulted in complete resolution of the skin lesions. EED is rarely reported in SLE, and its presentation and treatment is reviewed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Biopsy
  • Dapsone / therapeutic use*
  • Drug Therapy, Combination
  • Female
  • Humans
  • Hydroxychloroquine / therapeutic use
  • Lupus Erythematosus, Systemic / diagnosis*
  • Lupus Erythematosus, Systemic / drug therapy
  • Lupus Erythematosus, Systemic / pathology
  • Prednisone / therapeutic use
  • Treatment Outcome
  • Vasculitis, Leukocytoclastic, Cutaneous / diagnosis
  • Vasculitis, Leukocytoclastic, Cutaneous / drug therapy
  • Vasculitis, Leukocytoclastic, Cutaneous / pathology

Substances

  • Hydroxychloroquine
  • Dapsone
  • Prednisone

Supplementary concepts

  • Erythema elevatum diutinum