Ultrasound-guided viscosupplementation of subacromial space in elderly patients with cuff tear arthropathy using a high weight hyaluronic acid: prospective open-label non-randomized trial

Eur Radiol. 2011 Jan;21(1):182-7. doi: 10.1007/s00330-010-1894-4. Epub 2010 Jul 25.

Abstract

Objective: To assess if ultrasound (US)-guided viscosupplementation can reduce pain and improve function in elderly patients with cuff tear arthropathy.

Patients and methods: Ninety-three patients aged over 65 with grade 3 or above cuff tear arthropathy were included in this prospective open-label non-randomized trial. Institutional review board approval and informed consent were obtained. Thirty-three patients received intra-articular injections of sodium hyaluronate under US guidance. Sixty patients constituted the control group. Shoulder joint function was assessed with Constant scores (CS) and pain with a visual analogue scale (VAS).

Results: Compared with controls, treated patients reported a significant decrease in symptoms at 1 (mean CS 66±3.1 vs 37±6.9; mean VAS 1.9±1.2 vs 6.9±2.2), 2 (mean CS 65±3.2 vs 35±7.2; mean VAS 1.7±1.2 vs 6.8±2.5), 3 (mean CS 66±3.4 vs 33 6.1; mean VAS 2.3±1.2 vs 6.6±1.9), and 4 (mean CS 62±3.0 vs 34±6.5; mean VAS 3.3±1.4 vs 7.8±3.1) months, p<0.001. After 5 months there were no differences.

Conclusion: US-guided viscosupplementation is a beneficial therapeutic option in the first months of treatment.

Publication types

  • Clinical Trial

MeSH terms

  • Aged
  • Female
  • Humans
  • Hyaluronic Acid / therapeutic use*
  • Injections, Intra-Articular
  • Joint Diseases / diagnostic imaging*
  • Joint Diseases / therapy*
  • Male
  • Pain / drug therapy*
  • Shoulder Injuries
  • Shoulder* / diagnostic imaging
  • Shoulder* / pathology
  • Treatment Outcome
  • Ultrasonics
  • Ultrasonography
  • Viscosupplementation*
  • Viscosupplements / therapeutic use*

Substances

  • Viscosupplements
  • Hyaluronic Acid