Synchronous occurrence of metastatic Wilms tumor and ganglioneuroma

Pediatr Blood Cancer. 2010 Sep;55(3):562-5. doi: 10.1002/pbc.22553.

Abstract

We describe a 4-year-old female patient with a persistent paraspinal mass following chemotherapy for Wilms tumor. A discordant response to chemotherapy prompted biopsy of the persistent mass, which revealed a ganglioneuroma. This report highlights the synchronous occurrence of different tumors in the same patient, and suggests that repeat biopsies should be considered when contiguous tumor masses do not respond as expected.

Publication types

  • Case Reports

MeSH terms

  • Child, Preschool
  • Female
  • Ganglioneuroma / pathology*
  • Humans
  • Kidney Neoplasms / drug therapy
  • Kidney Neoplasms / pathology*
  • Lumbosacral Region
  • Neoplasms, Multiple Primary / pathology*
  • Retroperitoneal Neoplasms / secondary
  • Spinal Neoplasms / pathology*
  • Wilms Tumor / drug therapy
  • Wilms Tumor / secondary*