Caught in the Akt: regulation of Wnt signaling in the intestine

Gastroenterology. 2010 Sep;139(3):718-22. doi: 10.1053/j.gastro.2010.07.012. Epub 2010 Jul 24.
No abstract available

Publication types

  • Editorial
  • Comment

MeSH terms

  • Animals
  • Anti-Inflammatory Agents / therapeutic use
  • Cell Proliferation
  • Colitis / complications
  • Colitis / drug therapy
  • Colitis / enzymology*
  • Colitis / immunology
  • Colitis / pathology
  • Colon / drug effects
  • Colon / enzymology*
  • Colon / immunology
  • Colon / pathology
  • Colonic Neoplasms / enzymology
  • Colonic Neoplasms / pathology
  • Gastrointestinal Agents / therapeutic use
  • Humans
  • Intestinal Mucosa / drug effects
  • Intestinal Mucosa / enzymology*
  • Intestinal Mucosa / immunology
  • Intestinal Mucosa / pathology
  • Phosphatidylinositol 3-Kinases / metabolism
  • Phosphoinositide-3 Kinase Inhibitors
  • Phosphorylation
  • Protein Kinase Inhibitors / therapeutic use
  • Proto-Oncogene Proteins c-akt / antagonists & inhibitors
  • Proto-Oncogene Proteins c-akt / metabolism*
  • Signal Transduction* / drug effects
  • Stem Cells / enzymology*
  • Stem Cells / immunology
  • Stem Cells / pathology
  • T-Lymphocytes / enzymology
  • T-Lymphocytes / immunology
  • Wnt Proteins / metabolism*
  • beta Catenin / metabolism

Substances

  • Anti-Inflammatory Agents
  • Gastrointestinal Agents
  • Phosphoinositide-3 Kinase Inhibitors
  • Protein Kinase Inhibitors
  • Wnt Proteins
  • beta Catenin
  • Proto-Oncogene Proteins c-akt