A case of Y-autosome reciprocal translocation in a Holstein-Friesian bull

Cytogenet Genome Res. 2011;132(1-2):22-5. doi: 10.1159/000317089. Epub 2010 Jul 24.

Abstract

Cytogenetic evaluation of young bulls of the Polish Holstein-Friesian breed, tested before approving for use in artificial insemination, revealed a carrier of a Y-autosome reciprocal translocation. The applied chromosome banding techniques and fluorescence in situ hybridization (FISH), with the use of locus-specific BAC probes, facilitated description of the translocation as t(Y;21)(p11;q11). The bull presented normal development, including body weight and the size of testicles, as well as libido. Testosterone concentration at the age of 8 months was similar in the carrier and a normal bull of the same age, but at the age of 12 months the testosterone concentration appeared to be lower in the carrier.

MeSH terms

  • Animals
  • Cattle
  • Chromosomes, Artificial, Bacterial
  • In Situ Hybridization, Fluorescence
  • Male
  • Translocation, Genetic*
  • Y Chromosome*