Profile of post-traumatic epilepsy in Benin City, Nigeria

West Afr J Med. 2010 May-Jun;29(3):153-7. doi: 10.4314/wajm.v29i3.68212.

Abstract

Background: Post traumatic epilepsy is recurrent chronic seizures occurring after four weeks following brain injury. It commonly occurs after road traffic accidents thus making it a preventable cause of chronic seizures. The prevalence and pattern of this disorder is not known among Nigerian patients with epilepsy.

Objective: This study aimed at determining the prevalence of and predisposing type of head injury to developing post traumatic epilepsy.

Methods: We studied 244 consecutive patients with epilepsy attending the neurology clinic of a tertiary health facility in an urban Nigerian city by analyzing the details of their demographic and clinical data obtained with the aid of a structured questionnaire and from the Epilepsy Registry of a Neurology Unit between January and December 2006.

Results: Thirty-eight patients with a mean age of 38.6 +/- 7.3 years (age range 15- 75 years) had posttraumatic epilepsy comprising 15.57% of all cases of epilepsy. Thirty-three (86.8%) had closed head injury. Thirty-two (84.2%) of the patients had positive history of loss of consciousness. Twenty two patients (57.9%) sustained head injury from motor vehicle accidents. Majority of the patients had secondarily generalized seizures (73.7% of the cases). Twenty-seven (71.4%) of the 38 patients had seizure onset in the first year after brain injury. Depressed skull fracture (19/38; 50%) was the most common abnormal CT finding.

Conclusion: Post traumatic epilepsy contributes significantly to the number of patients with epilepsy presenting to our neurology services. There is need to educate people on the usefulness of seat-belts and helmets while driving.

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Aged
  • Anticonvulsants / administration & dosage*
  • Craniocerebral Trauma / complications*
  • Craniocerebral Trauma / epidemiology
  • Electroencephalography
  • Epilepsy, Post-Traumatic / diagnosis
  • Epilepsy, Post-Traumatic / drug therapy
  • Epilepsy, Post-Traumatic / epidemiology*
  • Epilepsy, Post-Traumatic / etiology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Nigeria / epidemiology
  • Phenytoin / administration & dosage*
  • Prevalence
  • Risk Factors
  • Sex Distribution
  • Time Factors
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Young Adult

Substances

  • Anticonvulsants
  • Phenytoin