Gynandroblastoma of the ovary having a typical morphological appearance: a case study

Jpn J Clin Oncol. 1991 Feb;21(1):62-8.

Abstract

A rare gynandroblastoma of the right ovary with a typical morphological appearance in a 65-year-old woman is reported. The tumor comprised both a granulosa cell element with a Call-Exner body and a Sertoli cell element. Pathologically, this case could be the most typical of all the world's established cases. Clinically, there were feminizing symptoms such as post-menopausal genital bleeding and endometrial cystic hyperplasia. Pre-operative serum hormonal assays indicated elevated levels of estrone, estradiol and testosterone, and low levels of gonadotropins. These returned to normal after surgery.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Female
  • Gonadal Steroid Hormones / metabolism
  • Humans
  • Neoplasms, Gonadal Tissue / metabolism
  • Neoplasms, Gonadal Tissue / pathology*
  • Neoplasms, Gonadal Tissue / surgery
  • Ovarian Neoplasms / metabolism
  • Ovarian Neoplasms / pathology*
  • Ovarian Neoplasms / surgery

Substances

  • Gonadal Steroid Hormones