Subunit exchange rates in Hepatitis B virus capsids are geometry- and temperature-dependent

Phys Chem Chem Phys. 2010 Nov 7;12(41):13368-71. doi: 10.1039/c0cp00692k. Epub 2010 Jul 30.

Abstract

Native tandem mass spectrometry reveals marked differences in the rates at which the two polymorphic forms of the HBV capsid exchange dimeric subunits with the soluble pool.

Publication types

  • Research Support, N.I.H., Intramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Capsid Proteins / chemistry*
  • Dimerization
  • Hepatitis B virus / metabolism*
  • Hydrogen-Ion Concentration
  • Mass Spectrometry
  • Protein Subunits / chemistry
  • Temperature

Substances

  • Capsid Proteins
  • Protein Subunits