Substituted dineolignans from Magnolia garrettii

J Nat Prod. 2010 Aug 27;73(8):1381-4. doi: 10.1021/np100263e.

Abstract

In the course of a study on lignan profiles of tropical and subtropical members of the Magnoliaceae, Magnolia garrettii, an evergreen tree known from northern Thailand, Vietnam, and southern Yunnan (China), was investigated. The work resulted in the isolation of two dimeric lignans from the dichloromethane extract of the leaves of M. garrettii, garrettilignan A (1) and garrettilignan B (2), each substituted with two additional p-allylphenolic moieties. Garrettilignans A (1) and B (2) represent new skeletal types within the neolignan class. Additionally, four known neolignans, magnolol, honokiol, 4'-methylhonokiol, and obovatol, were identified.

MeSH terms

  • Austria
  • Biphenyl Compounds / chemistry
  • Biphenyl Compounds / isolation & purification
  • Lignans / chemistry
  • Lignans / isolation & purification*
  • Magnolia / chemistry*
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Phenyl Ethers / chemistry
  • Phenyl Ethers / isolation & purification
  • Plant Leaves / chemistry

Substances

  • Biphenyl Compounds
  • Lignans
  • Phenyl Ethers
  • garrettilignan A
  • garrettilignan B
  • magnolol
  • honokiol
  • obovatol