Diffusion-weighted echo planar imaging in patients with recent myocardial infarction

Eur Radiol. 2011 Jan;21(1):46-53. doi: 10.1007/s00330-010-1912-6. Epub 2010 Aug 1.

Abstract

Objective: To evaluate a diffusion-weighted (DW) black blood MR sequence for the detection of myocardium signal abnormalities in patients with recent myocardial infarction (MI).

Methods: A DW black blood EPI sequence was acquired at 1.5 T in 12 patients with recent MI. One slice per patient was acquired with b=0 and b=50 s/mm2. A standard short tau inversion recovery (STIR) T2-weighted sequence was acquired at the same level. Viability was assessed with delayed-enhancement sequences. Images were analyzed qualitatively and quantitatively. A non parametric Wilcoxon test was used for statistical analysis, with a significance level of P<.05.

Results: The mean quality of blood suppression was higher on DW EPI images than on STIR T2-weighted images (3.9±0.3 and 3.0±0.7, respectively; P=0.01). Myocardial high signal areas were detected in respectively 100% (12/12) and 67% (8/12) of the patients on DW EPI and STIR T2-weighted images. The four patients (33%) with false-negative STIR T2 findings all had high signal areas on DW EPI images corresponding to the location of the MI on the delayed-enhanced images.

Conclusion: DW EPI sequences are a feasible alternative to standard STIR T2-weighted sequences for detecting myocardium high signal areas in patients with recent MI.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Diffusion Magnetic Resonance Imaging*
  • Echo-Planar Imaging / methods*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Myocardial Infarction / diagnostic imaging*
  • Radiography