Abstract
Three new aromatic epsilon-lactones, aggregatins A (1), B (2), and C (3), a new naphthoquinone derivative, aggregatin D (4), and three known anthraquinones, 2-methylanthraquinone, 7-methoxy-2-methylanthraquinone, and 7-hydroxy-2-methylanthraquinone, were isolated from the tubers of Sinningia aggregata (Gesneriaceae). Compounds 1 and 4 and the anthraquinones showed marginal antimicrobial activity.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anthraquinones / chemistry
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Anthraquinones / isolation & purification*
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Anthraquinones / pharmacology
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Anti-Infective Agents / chemistry
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Anti-Infective Agents / isolation & purification*
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Anti-Infective Agents / pharmacology
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Brazil
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Escherichia coli / drug effects
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Lactones / chemistry
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Lactones / isolation & purification*
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Lactones / pharmacology
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Magnoliopsida / chemistry*
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Microbial Sensitivity Tests
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Molecular Structure
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Naphthoquinones / chemistry
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Naphthoquinones / isolation & purification*
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Naphthoquinones / pharmacology
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Nuclear Magnetic Resonance, Biomolecular
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Pseudomonas aeruginosa / drug effects
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Staphylococcus / drug effects
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Yeasts / drug effects
Substances
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Anthraquinones
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Anti-Infective Agents
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Lactones
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Naphthoquinones
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aggregatin A
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aggregatin B
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aggregatin C
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aggregatin D
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2-methylanthraquinone