[A case of cardiac sarcoidosis occurring during combination therapy by IFN alpha and ribavirin for chronic hepatitis C]

Nihon Shokakibyo Gakkai Zasshi. 2010 Aug;107(8):1319-27.
[Article in Japanese]

Abstract

A 72-year-old woman received combination therapy with peginterferon alpha and ribavirin for treatment of chronic hepatitis C. Approximately 40 weeks after starting treatment, she developed an eruption in the left inner canthus and sarcoidosis was diagnosed after biopsy of the eruption. Combination therapy was discontinued, and further detailed examinations revealed bilateral hilar lymphadenopathy, uveitis, and complete atrioventricular block. A permanent cardiac pacemaker was implanted, and her sarcoidosis improved upon administration of corticosteroids.

Publication types

  • Case Reports
  • English Abstract
  • Review

MeSH terms

  • Aged
  • Antiviral Agents / adverse effects*
  • Cardiomyopathies / etiology*
  • Female
  • Hepatitis C, Chronic / drug therapy*
  • Humans
  • Interferon-alpha / adverse effects*
  • Ribavirin / adverse effects*
  • Sarcoidosis / etiology*

Substances

  • Antiviral Agents
  • Interferon-alpha
  • Ribavirin