Characterization of Shiga toxin-producing Escherichia coli isolated from dairy cows in Argentina

Lett Appl Microbiol. 2010 Oct;51(4):377-82. doi: 10.1111/j.1472-765X.2010.02904.x. Epub 2010 Aug 3.

Abstract

Aims: To feno-genotypically characterize the Shiga toxin-producing Escherichia coli (STEC) population in Argentinean dairy cows.

Methods and results: From 540 STEC positive samples, 170 isolates were analyzed by multiplex PCR and serotyping. Of these, 11% carried stx1, 52% stx2 and 37% stx1/stx2. The ehxA, saa and eae were detected in 77%, 66% and 3%, respectively. Thirty-five per cent of strains harboured the profile stx1, stx2, saa, ehxA and 29% stx2, saa, ehxA. One hundred and fifty-six strains were associated with 29 different O serogroups, and 19 H antigens were distributed among 157 strains. STEC O113:H21, O130:H11 and O178:H19 were the most frequently found serotypes. The STEC O157:H7 were detected in low rate and corresponded to the stx2(+) , eae(+) , ehxA(+) virulence pattern.

Conclusions: We detected a diversity of STEC strains in dairy cattle from Argentina, most of them carrying genes linked to human disease.

Significance and impact of the study: The non-O157 STEC serotypes described in this study are associated worldwide with disease in humans and represent a risk for the public health. For this, any microbiological control in dairy farms should be targeted not only to the search of O157:H7 serotype.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Argentina
  • Cattle
  • Cattle Diseases / epidemiology
  • Cattle Diseases / microbiology*
  • Dairying*
  • Escherichia coli Infections / epidemiology
  • Escherichia coli Infections / microbiology
  • Escherichia coli Infections / veterinary*
  • Escherichia coli O157 / classification
  • Escherichia coli O157 / genetics
  • Escherichia coli O157 / isolation & purification
  • Escherichia coli Proteins / genetics
  • Humans
  • Polymerase Chain Reaction / methods
  • Polymerase Chain Reaction / veterinary*
  • Serotyping
  • Shiga Toxin 2 / genetics
  • Shiga Toxins / genetics
  • Shiga-Toxigenic Escherichia coli / classification*
  • Shiga-Toxigenic Escherichia coli / genetics
  • Shiga-Toxigenic Escherichia coli / isolation & purification*
  • Virulence / genetics
  • Virulence Factors / genetics*
  • Virulence Factors / metabolism

Substances

  • Escherichia coli Proteins
  • Shiga Toxin 2
  • Shiga Toxins
  • Virulence Factors