A comparative study on suture versus cuff anastomosis in mouse cervical cardiac transplant

Exp Clin Transplant. 2010 Sep;8(3):245-9.

Abstract

Objectives: To compare the cuff technique to traditional suture technique in establishing cervical heart transplant model in mice.

Materials and methods: Eighty transplants were performed by 1 surgeon, 40 using the cuff technique, and 40 using the suture technique, under the same circumstances.

Results: The cuff approach was significantly superior to conventional suture anastomosis in higher surgical successful rate, less surgery, and less ischemic time (P < .05). Suture anastomosis required an intensive microsurgical training and at least a 16x surgical microscope, while the cuff anastomosis required less learning time and a 10x surgical microscope.

Conclusions: The cuff technique is the preferred method in cervical heart transplant model in mice.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anastomosis, Surgical
  • Animals
  • Cold Ischemia
  • Female
  • Heart Transplantation / methods*
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Microsurgery*
  • Motor Skills
  • Suture Techniques*
  • Time Factors