Brønsted acid differentiated metal catalysis by kinetic discrimination

Chem Commun (Camb). 2011 Jan 7;47(1):304-6. doi: 10.1039/c0cc02167a. Epub 2010 Aug 17.

Abstract

A Brønsted acid differentiated metal catalyzed hydrogenation has been developed. A combinatorial variation of chiral triflylamides with achiral metal complexes results in a highly active catalyst for the asymmetric reduction.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acids / chemistry*
  • Amides / chemistry
  • Catalysis
  • Hydrogenation
  • Iridium / chemistry*
  • Kinetics
  • Molecular Structure
  • Organometallic Compounds / chemistry*
  • Quinolines / chemical synthesis*
  • Quinolines / chemistry
  • Stereoisomerism

Substances

  • Acids
  • Amides
  • Organometallic Compounds
  • Quinolines
  • Iridium