Abstract
Two new heterocyclic compounds, bretschneiderazines A and B (1, 2), three new aromatic diglycosides, bretschneiderosides A-C (3-5), and three known aromatic diglycosides, 6-8, were isolated from Bretschneidera sinensis. The structure of bretschneiderazine A (1) was confirmed by single-crystal X-ray diffraction analysis. Bretschneiderazine A (1) showed moderate activity against the NCI-H446 cell line.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antineoplastic Agents, Phytogenic / chemistry
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Antineoplastic Agents, Phytogenic / isolation & purification*
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Antineoplastic Agents, Phytogenic / pharmacology
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Crystallography, X-Ray
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Drug Screening Assays, Antitumor
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Drugs, Chinese Herbal / chemistry
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Drugs, Chinese Herbal / isolation & purification*
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Drugs, Chinese Herbal / pharmacology
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Glycosides / chemistry
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Glycosides / isolation & purification*
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Glycosides / pharmacology
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HCT116 Cells
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HL-60 Cells
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Heterocyclic Compounds, 2-Ring / chemistry
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Heterocyclic Compounds, 2-Ring / isolation & purification*
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Heterocyclic Compounds, 2-Ring / pharmacology
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Humans
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Molecular Structure
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Plant Stems / chemistry
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Plants, Medicinal / chemistry*
Substances
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Antineoplastic Agents, Phytogenic
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Drugs, Chinese Herbal
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Glycosides
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Heterocyclic Compounds, 2-Ring
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bretschneiderazine A
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bretschneiderazine B
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bretschneideroside A
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bretschneideroside B
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bretschneideroside C