Orientations of the Bacteroides fragilis capsular polysaccharide biosynthesis locus promoters during symbiosis and infection

J Bacteriol. 2010 Nov;192(21):5832-6. doi: 10.1128/JB.00555-10. Epub 2010 Aug 20.

Abstract

Orientations of the seven invertible polysaccharide biosynthesis locus promoters of Bacteroides fragilis were determined from bacteria grown in vitro, from feces of monoassociated and complex colonized mice, and from B. fragilis-induced murine abscesses. Bacteria grown in vivo have greater variability in orientation of polysaccharide locus promoters than culture-grown organisms.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Abscess / microbiology
  • Animals
  • Bacteriological Techniques
  • Bacteroides Infections / microbiology*
  • Bacteroides fragilis / genetics
  • Bacteroides fragilis / metabolism*
  • Feces / microbiology
  • Gene Expression Regulation, Bacterial / physiology
  • Mice
  • Polysaccharides, Bacterial / biosynthesis*
  • Polysaccharides, Bacterial / genetics
  • Promoter Regions, Genetic
  • Symbiosis*

Substances

  • Polysaccharides, Bacterial