Marjolin's ulcer: Sequelae of mismanaged chronic cutaneous ulcers

Adv Skin Wound Care. 2010 Sep;23(9):414-6. doi: 10.1097/01.ASW.0000383211.18782.2a.

Abstract

Objective: This study was to evaluate the current pattern and risk factors of Marjolin's ulcer in the authors' setting.

Settings and participants: Twenty-one patients with histological diagnosis of skin malignancy at the University of Calabar Teaching Hospital, Calabar, Nigeria.

Methods: Presented are patients with histologic diagnosis of Marjolin's seen in the University of Calabar Teaching Hospital, Calabar, Nigeria from January 2007 through December 2007.

Results: Five patients (3 men and 2 women) with Marjolin's ulcer whose ages ranged from 32 to 70 years (mean 46.6 years) accounted for 45.5% of squamous cell carcinoma. All the patients suffered traumatic injuries (4 lower limb injuries from road traffic accidents and 1 puncture wound of the upper limb) and the latency was 21.4 years.

Conclusions: Chronic trauma-induced limb ulceration is the leading risk factor for Marjolin's ulcer. Health education, early detection, and proper management of chronic wounds would improve outcome.

MeSH terms

  • Adult
  • Aged
  • Arm Injuries / complications
  • Carcinoma, Squamous Cell / etiology
  • Chronic Disease
  • Female
  • Humans
  • Leg Injuries / complications
  • Male
  • Middle Aged
  • Neoplasms, Post-Traumatic / etiology*
  • Neoplasms, Post-Traumatic / therapy
  • Risk Factors
  • Skin / injuries*
  • Skin / pathology
  • Skin Neoplasms / etiology*
  • Skin Neoplasms / pathology
  • Skin Ulcer / complications*
  • Skin Ulcer / pathology
  • Skin Ulcer / therapy*
  • Treatment Failure