Non-conjugated chenodeoxycholate induces severe mitochondrial damage and inhibits bicarbonate transport in pancreatic duct cells

Gut. 2011 Jan;60(1):136-8. doi: 10.1136/gut.2009.192153. Epub 2010 Aug 23.
No abstract available

Publication types

  • Comment
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bicarbonates / metabolism
  • Biological Transport / drug effects
  • Chenodeoxycholic Acid / pharmacology*
  • Glycochenodeoxycholic Acid / pharmacology
  • Guinea Pigs
  • Mitochondria / drug effects*
  • Pancreatic Ducts / drug effects*

Substances

  • Bicarbonates
  • Chenodeoxycholic Acid
  • Glycochenodeoxycholic Acid