Antenatal embolization of a large chorioangioma by percutaneous Glubran 2 injection

Ultrasound Obstet Gynecol. 2010 Dec;36(6):773-5. doi: 10.1002/uog.8806. Epub 2010 Nov 12.

Abstract

We describe a case of a large chorioangioma diagnosed at 18 weeks' gestation. Because of advanced fetal heart failure at 23 weeks' gestation, embolization of the chorioangioma's vessels was performed by percutaneous injection of Glubran 2 surgical glue. There was no immediate secondary effect of treatment. Devascularization was complete and durable. Signs of fetal cardiac failure normalized after 1 month and a healthy infant was delivered at 38 weeks. To our knowledge this is the first reported case of perinatal survival after successful embolization of a chorioangioma using tissue glue.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cyanoacrylates / administration & dosage*
  • Embolization, Therapeutic / methods*
  • Female
  • Fetal Diseases / therapy
  • Gestational Age
  • Heart Failure / therapy
  • Hemangioma / diagnostic imaging
  • Hemangioma / therapy*
  • Humans
  • Infant, Newborn
  • Placenta Diseases / diagnostic imaging
  • Placenta Diseases / therapy*
  • Pregnancy
  • Pregnancy Complications, Neoplastic / diagnostic imaging
  • Pregnancy Complications, Neoplastic / therapy*
  • Pregnancy Outcome
  • Tissue Adhesives / administration & dosage*
  • Ultrasonography

Substances

  • Cyanoacrylates
  • Tissue Adhesives
  • glubran 2