Impact of a palliative care consultation team on cancer-related symptoms in advanced cancer patients referred to an outpatient supportive care clinic

J Pain Symptom Manage. 2011 Jan;41(1):49-56. doi: 10.1016/j.jpainsymman.2010.03.017. Epub 2010 Aug 24.

Abstract

Context: Patients with advanced cancer may develop severe physical and psychosocial symptoms. There are limited data on the impact of an outpatient palliative consultation (PC) team on cancer-related symptoms.

Objectives: To study the impact of the PC on symptoms in patients with advanced cancer receiving outpatient palliative care.

Methods: Four hundred six consecutive patients referred to a supportive care outpatient center (OPC) from January 2006 to June 2007 with complete Edmonton Symptom Assessment Scale (0-10 scale) at the initial and follow-up visits were reviewed. Patient characteristics, change of symptoms at follow-up visit, and response rate were analyzed. Using logistic regression models, the predictors of improvement of pain and fatigue were assessed.

Results: Median age was 59 years; 53% were female. Median interval between visits was 15 days. Mean scores at baseline and follow-up visits were fatigue 6.8 and 5.3 (P<0.0001), pain 5.3 and 4.1 (P<0.0001), depression 3.2 and 2.5 (P<0.0001), anxiety 3.7 and 2.8 (P<0.0001), dyspnea 2.7 and 2.5 (P=0.05), sleep 5 and 4 (P<0.0001), and well-being 5.2 and 4.4 (P<0.0001). Dyspnea (odds ratio and P-value, 0.90, 0.03), nausea (0.92, 0.06), and depression (0.91, 0.04) were associated with improvement in fatigue; drowsiness (1.10, 0.04), and feeling of well-being (0.87, 0.02) were associated with improvement in pain.

Conclusion: The initial consult by PC achieved significant symptom improvement in patients receiving treatment in the OPC. Further prospective studies are needed.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Ambulatory Care
  • Ambulatory Care Facilities
  • Anxiety / diagnosis
  • Anxiety / epidemiology
  • Anxiety / prevention & control*
  • Causality
  • Comorbidity
  • Fatigue / diagnosis
  • Fatigue / epidemiology
  • Fatigue / prevention & control*
  • Feeding and Eating Disorders / diagnosis
  • Feeding and Eating Disorders / epidemiology
  • Feeding and Eating Disorders / prevention & control
  • Female
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Nausea / diagnosis
  • Nausea / epidemiology
  • Nausea / prevention & control
  • Neoplasms / diagnosis
  • Neoplasms / epidemiology
  • Neoplasms / nursing*
  • Pain / diagnosis
  • Pain / epidemiology
  • Pain / prevention & control*
  • Palliative Care / statistics & numerical data*
  • Patient Care Team / statistics & numerical data*
  • Referral and Consultation / statistics & numerical data*
  • Retrospective Studies
  • Risk Factors
  • Terminal Care
  • Texas / epidemiology
  • Treatment Outcome