Association of preanesthesia hypertension with adverse outcomes

J Cardiothorac Vasc Anesth. 2010 Dec;24(6):927-30. doi: 10.1053/j.jvca.2010.06.022.

Abstract

Objective: To investigate the incidence of preanesthesia hypertension, case cancellation for hypertension, and association with postoperative outcomes.

Design: Retrospective descriptive, univariate, and multivariate analyses of electronic anesthesia and hospital records.

Setting: A large urban academic medical center.

Participants: Adult elective surgical patients with preinduction blood pressure (BP) >140/90 mmHg during calendar years 2002 to 2008.

Interventions: None.

Measurements and main results: Preinduction hypertension was present in 21,126 of 209,985 (10%) patients, and the incidence of adverse outcomes (elevated troponin or in-hospital death) was 1.3% overall and 2.8% for the subset of patients with baseline systolic BP >200 mmHg. Independent predictors of adverse outcome included increased baseline systolic BP, intraoperative diastolic BP <85 mmHg, increased intraoperative heart rate, blood transfusion, and anesthetic technique, controlling for standard risk factors. A total of 69 hypertensive patients (0.3%) had surgery cancelled before the induction of anesthesia; 29 of these cancellations occurred among the 1,330 patients with baseline SBP >200 mmHg (2.2%). Among 42 "cancelled" patients who returned for surgery hours to years later, the average preinduction BP was 192/102 mmHg, and adverse cardiovascular outcomes occurred in 4.8%.

Conclusions: The increasing severity of preinduction hypertension was an independent risk factor for postoperative myocardial injury/infarction or in-hospital death. Only a small percentage of cases with patients presenting with severe hypertension were cancelled, and the delay of surgery did not result in interval normalization of blood pressure.

MeSH terms

  • Adult
  • Aged
  • Anesthesia*
  • Blood Pressure / physiology
  • Cardiac Surgical Procedures / adverse effects*
  • Cardiac Surgical Procedures / mortality
  • Electronic Health Records
  • Female
  • Heart Rate / physiology
  • Hospital Mortality
  • Humans
  • Hypertension / complications*
  • Hypertension / epidemiology
  • Hypertension / mortality
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Preoperative Period*
  • Retrospective Studies
  • Risk Factors
  • Treatment Outcome
  • Troponin / blood

Substances

  • Troponin